Knowledge Base
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Types and Applications of Ion-Pair Reagents in Liquid Chromatography
Explore the types of ion-pair reagents used in liquid chromatography, including traditional, volatile, and elution agents, and their applications for improved peak retention and shape. -
New Safety Precautions for HPLC: Handling Extreme Heat, Lightning, and Heavy Rain
In addition to making people uncomfortable, high temperatures can also affect our HPLC systems. Have you noticed that summer is a season when HPLC problems frequently occur? Let's take a... -
Spotlight: Welch Ghost Buster Columns High-Pressure Endurance Test
Introduction In liquid chromatography analysis, when buffer salts or acidic additives are used in the mobile phase and gradient elution is employed, it is common to encounter inexplicable peaks on... -
Immunoaffinity Cartridges for Mycotoxins: Common Questions and Answers
Mycotoxin Immunoaffinity Cartridges—These cartridges adsorb mycotoxins based on the specific interaction between antigens and antibodies. For first-time users, there are often many questions. The most frequently asked questions include: 'How... -
Usage Precautions for Welch Sugar Columns
Precautions for Using Welch Sugar Columns Welch Sugar Columns are tightly packed with resin in an expanded form. If the sample has been properly pre-treated, most issues are related to... -
Why is the detection limit 3 times the signal-to-noise ratio
The detection limit and quantitation limit are important attributes of analytical methods. However, in actual scientific research, many colleagues only know that the detection limit is 3 times the signal-to-noise... -
Cleaning and Passivation of Liquid Chromatography
Learn how to clean, passivate, and maintain HPLC systems to remove contamination, prevent corrosion, and improve peak shape for optimal performance. -
Distinguishing Key Time Concepts in Chromatography Analysis
Learn about essential chromatography time concepts like retention, dead, adjusted retention, relative retention, and delay time for accurate analysis and method development. -
Understanding Pesticide Residue: A Scientific Perspective
As people continue to pursue a green and healthy lifestyle, pesticide residues are receiving increasing attention. Are pesticide residues really that terrifying? Are the fruits and vegetables we encounter daily... -
Intrinsic Dissolution Testing Is Here， Are You Ready?
For the new inherent dissolution testing, we find ourselves both familiar and unfamiliar. We are familiar with it because it falls within the realm of dissolution, yet unfamiliar due to... -
Introduction to High-Capacity Ion Exchange Chromatography Media
Ion exchange chromatography, as the most classic separation mode in the field of biomacromolecule separation and purification, currently occupies a considerable market share. The basic mechanism for separating proteins using... -
One column one method vs one column multi-method, which one is more effiective?
One column one method vs one column multi-method, which one is more effective? Scenario 1: Ah, what on earth is this unknown peak? It's been interfering with my target peak...
