Your Chiral Separation Partner across All Scales: New Blossmate Chiral Series Now Available!
Summary
Welch Materials releases new Blossmate series chiral stationary phases, from analytical columns, preparative columns, to bulk media (packing materials). It will replace our existing Ultisil chiral series to be your new chiral separation partner across all scales, bringing high selectivity, high loading capacity, and consistent and reproducible separation results.
Product Overview
Our Blossmate chiral stationary phases are designed for high-performance enantiomeric separations in analytical, preparative, and bulk purification scale. Available in both coated and immobilized polysaccharide phases, Blossmate chiral series products deliver selectivity, reproducibility, and scalability from R&D through commercial purification.
Phase Options
- Coated phases: 5 distinct coated polysaccharide CSP chemistries: Amy-D, Cellu-D, Amy-S, Cellu-J, and Cellu-Z. Each chemistry is supplied in both normal-phase and reversed-phase variants.
- Immobilized phases: 4 immobilized polysaccharide CSP chemistries: IMMA, IMMB, IMMC, IMMG.
| Welch Chiral Product | Phase | Structure | Type | Equivalent |
|---|---|---|---|---|
| Blossmate Amy-D | Amylose tris(3,5-dimethylphenyl carbamate) |  |
Coated | AD |
| Blossmate Cellu-D | Cellulose tris(3,5-dimethylphenyl carbamate) |  |
Coated | OD |
| Blossmate Amy-S | Amylose tris((S)-α-methylbenzyl carbamate) |  |
Coated | AS |
| Blossmate Cellu-J | Cellulose tris(4-methylbenzoate) |  |
Coated | OJ |
| Blossmate Cellu-Z | Cellulose tris(3-chloro-4-methylphenyl carbamate) |  |
Coated | OZ |
| Blossmate IMMA | Amylose tris(3,5-dimethylphenyl carbamate) |  |
Immobilized | IA |
| Blossmate IMMB | Cellulose tris(3,5-dimethylphenyl carbamate) |  |
Immobilized | IB |
| Blossmate IMMC | Cellulose tris(3,5-dichlorophenyl carbamate) |  |
Immobilized | IC |
| Blossmate IMMG | Amylose tris(3-chloro-5-methylphenyl carbamte) |  |
Immobilized | IG |
Key Advantages
- Excellent selectivity — Polysaccharide-based CSPs in the Blossmate chiral family exhibit broad and robust chiral recognition across diverse classes of molecules, improving enantiomeric resolution for challenging targets.
- High efficiency & superior separation — Columns consistently produce strong peak shape, high theoretical plate counts, and reproducible retention behavior run-to-run and batch-to-batch.
- Scale-up capability — Identical stationary-phase chemistries are available across analytical, preparative, and bulk formats to support direct scale-up and process intensification with minimal re-optimization.
- SFC and HPLC compatibility — Preparative column hardware is SFC-compatible by design; the same column hardware supports both preparative SFC and HPLC workflows without the need for separate fittings or special vessels.
Modes of Use
Blossmate chiral columns and media support the full range of commonly used chiral separation modes: normal-phase, reversed-phase, polar organic, and SFC (supercritical fluid chromatography), enabling flexible method development for both polar and nonpolar targets.
Specifications
- Analytical columns: 4.6 mm ID; lengths 150 mm or 250 mm; particle sizes 5 µm or 10 µm.
- Preparative columns: IDs 10 mm, 21.2 mm, 30 mm, or 50 mm; length 250 mm; particle sizes 5 µm or 10 µm.
- Bulk media: particle sizes 5 µm or 10 µm, supplied for packing in custom housings or process vessels.
- For customized dimensions, please contact us directly.
Transition from Ultisil
Blossmate chiral columns replace our existing Ultisil chiral columns (which will no longer be available on most sales channel) as the primary chiral offering. In case you still have a need for Ultisil chiral columns, please contact our sales team directly.
Ordering & Technical Support
Welch Materials provides application support for method scouting, scale-up guidance, and packing recommendations. For product inquiries, application evaluations, or custom dimension requests, please contact our sales team at info@welchmat.com.