News
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Chromatographic Column Selection in HPLC Method Development (Part 1)
In the development of reversed-phase liquid chromatography (RPLC) methods, the selection of chromatographic columns is generally approached through two methods: one based on practical experience and the other rooted in... -
SEC (Size Exclusion Chromatography)
Overview SEC (Size Exclusion Chromatography) is a technique that separates molecules of interest by their molecular size. There are 2 types of SEC separation known as Gel Filtration Chromatography... -
Can Normal-Phase Chromatography Be Combined with Mass Spectrometry?
Recently, I have been involved in a project focused on the development of isomers of lycopene, a natural pigment found in food that belongs to the carotenoid family. Over the... -
LP-C18 : Can it Separate Isomers and Chiral Diastereomers?
Following the previous article “1Can LP Columns Only Resist Strong Acids?” this article takes a user-centric approach, guiding everyone in a clear and in-depth exploration to understand the manufacturer’s design...