Knowledge Base

This article explores how using Xtimate® Sugar-H and Sugar-Ca columns in series can significantly enhance resolution in sugar analysis. With real application cases in fermentation broth and pharmaceutical solutions, it demonstrates improved separation performance while maintaining safe pressure levels—offering a practical solution for challenging HPLC sugar separations.

This Q&A recap from our May 22 webinar covers essential questions on ADC analysis using Advanchrom HIC-Butyl columns, with expanded expert responses offering deeper insights into best practices and technical considerations.

Discover Welch HPLC columns featured in the 2025 Chinese Pharmacopoeia, with applications and specs for pharmaceutical analysis.

Introduce the principle of amino columns (nh2 columns) and the guidelines for optimizing amino column performance in reversed-phase and normal-phase mode.

In this article, we explore how particle size affects resolution in liquid chromatography through two real-world applications, and analyze why these cases show different results from common belief.

Discover how derivatization technology in HPLC boosts detection and separation performance, addressing analytical challenges with innovative techniques and real-world applications.

Welch Xtimate Sugar Columns offer precise carbohydrate separation via ion coordination exchange, with easy regeneration and protection from metal ion interference.

Discover effective strategies and case studies for retaining polar compounds in chromatography, including column selection and practical applications.

Explore specialized chromatography columns with shape selectivity and spatial interactions for effective isomer separation, including phenyl/PFP, amide, and C8 columns, etc.

Discover CMPA method insights for enantiomer separation using cyclodextrin additives, optimizing conditions with practical tips for efficient chromatographic performance.

Discover best practices for C18 column activation and maintenance, including tips to achieve reliable and efficient analytical results.