News
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Analysis of Cephalosporins: Unique Effects of Diamond-Like Carbon Columns
It is well known that antibiotics play a crucial role in treating infectious diseases in humans. Among them, cephalosporins, a series of semi-synthetic antibiotics, are widely used in clinical practice... -
New packaging for Welch Materials HPLC columns enhanced-security-eco-friendly-and-convenient
Please be aware that Welch Materials will use the brand-new designed packing for our chromatography columns. So both the new and old packing might be used during this time. We... -
【New Product Release】Novel Macroporous Polymer-Based Ion Exchange Medium
Ion exchange chromatography is the most commonly used method for the separation and purification of biomacromolecules. The target protein interacts electrostatically with the ion exchange resin, and separation is achieved... -
Biopolymer Analysis with Welch Xtimate C4 300Å HPLC Column Launch!
Welch Xtimate® C4 300Å HPLC column, which offers typical reverse-phase separation and features high column efficiency, long lifespan, and wide pH tolerance. -
New Product Release: Agarose-Based High-Performance Protein A Affinity Chromatography Resin Packing Materials
Monoclonal antibodies have uniform chemical properties and strong specificity, making them a widely used biopharmaceutical. Protein A affinity chromatography resin packing materials, due to its specific binding properties and powerful... -
Tirzepatide Purification by Xtimate C8
This article summaries two applications for process optimization for purifying tirzepatide API with different purity levels. -
Chromatographic Column Selection in HPLC Method Development (Part 1)
In the development of reversed-phase liquid chromatography (RPLC) methods, the selection of chromatographic columns is generally approached through two methods: one based on practical experience and the other rooted in... -
Determination of mannitol content with Ultisil HILIC-Amide
Test Report Sample Information Sample Name Mannitol Project Number 20230908-854-01 Sample Batch No. / Sample Characteristics White powder Sample Receipt Date 09/12/2023 Testing Period 09/18/2023 ~ 09/20/2023 Standard Sample Information Name... -
SEC (Size Exclusion Chromatography)
Overview SEC (Size Exclusion Chromatography) is a technique that separates molecules of interest by their molecular size. There are 2 types of SEC separation known as Gel Filtration Chromatography... -
His-tagged protein purification with Ni column, so simple!
Introduction In 1975, Porath et al. proposed a new purification method - immobilized metal chelate chromatography. This method uses coordination-chelation interaction of metal ions (Ni2+, Cu2+, etc.) with residues... -
Separation Method of Protein
Proteins exist in tissues or cells as complex mixtures and each type of cell contains thousands of different proteins. However, there is no single method can remove any type... -
Oxidative damage in GC column
Oxygen is a hazardous substance for most of the capillary columns. At room temperature, the column will not be damaged. But as the column temperature increases, the column will be...
