База знаний

Chromatographic analysis for peptide drugs are important for ensuring product quality and safety. In this article, we introduce our solutions for peptide drug analysis, including the chiral analysis of protected amino acids, the determination of peptide related substances, the analysis of peptide aggregates by SEC, and the evaluation of amino acid ratios using the Welch Ultisil Amino Acid Method Kit.

Isomer separation is one of the most challenging tasks in chromatography. In this article, we evaluate the chromatographic performance of three Welch Materials’ Ultisil stationary phases—PFP, Alk-C18, and XS-C18—on the separation of isomeric derivatives and analogs of antharaquinone.