Knowledge Base

Chromatographic analysis for peptide drugs are important for ensuring product quality and safety. In this article, we introduce our solutions for peptide drug analysis, including the chiral analysis of protected amino acids, the determination of peptide related substances, the analysis of peptide aggregates by SEC, and the evaluation of amino acid ratios using the Welch Ultisil Amino Acid Method Kit.

In this article, we present solutions for the chromatographic analysis of biological samples from Welch Materials, covering SEC, RPLC, HIC, and ion exchange chromatography, with multiple applications of peptides, nucleic acids, antibodies, and proteins.

Biopharmaceutical integrity relies on precise molecular size characterization. In this article, we explain how Welch Xtimate Bio SEC columns mitigate non-specific adsorption in SEC compared with competitors, and provide guides on optimizing mobile phase in different SEC assays.

In this article, we explore the analytical challenges of recombinant humanized type III collagen and show how Xtimate Bio SEC columns support accurate purity and aggregate profiling. The article also highlights the role of SEC in quality control and demonstrates strong chromatographic performance for collagen characterization.