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In this article, we explore further how matrix effects affects recovery results in mass spectrometry analyses by hindering preparation loss, and discuss when it should be corrected by using calibration curves prepared by blank matrices.
Discover practical strategies to tackle matrix effects in mass spectrometry, from purification to isotopic standards, ensuring accurate and reliable results.
![[Readers Insight] Matrix Effects in Mass Spectrometry: Why They Matter](//www.welch-us.com/cdn/shop/articles/matrix-effect-2-1080-922_b1c87dc5-0653-4cb6-afe0-a6d0f011eced_535x.jpg?v=1759999506)
![[Readers Insight] Matrix Effects in Mass Spectrometry: Why They Matter](//www.welch-us.com/cdn/shop/articles/matrix-effect-2-1080-922_b1c87dc5-0653-4cb6-afe0-a6d0f011eced_345x345@2x.jpg?v=1759999506)
![[Reader Insight] Matrix Effects in Mass Spectrometry Analysis: Causes and Solutions](//www.welch-us.com/cdn/shop/articles/matrix-effects-1080-1121_7dfbabd3-34cb-4b9a-8d4d-c02195558945_345x345@2x.webp?v=1765510097)
![[Readers Insight] Matrix Effects in Mass Spectrometry: Why They Matter](http://www.welch-us.com/cdn/shop/articles/matrix-effect-2-1080-922_b1c87dc5-0653-4cb6-afe0-a6d0f011eced_535x.jpg?v=1759999506)
![[Readers Insight] Matrix Effects in Mass Spectrometry: Why They Matter](http://www.welch-us.com/cdn/shop/articles/matrix-effect-2-1080-922_b1c87dc5-0653-4cb6-afe0-a6d0f011eced_345x345@2x.jpg?v=1759999506)
![[Reader Insight] Matrix Effects in Mass Spectrometry Analysis: Causes and Solutions](http://www.welch-us.com/cdn/shop/articles/matrix-effects-1080-1121_7dfbabd3-34cb-4b9a-8d4d-c02195558945_345x345@2x.webp?v=1765510097)