While synthetic intermediates are not themselves in the final API, their stereochemical purity affects product quality greatly. In this article, we present application notes of five typical synthetic intermediates, witnessing how Blossmate chiral columns successfully separate them from their enantiomers.
Chirality can mean the difference between medicine and catastrophe. In this article, we summarize the necessity of enantiomeric precision and explain how our Blossmate chiral columns offer flexible, MS-compatible solutions for analytical and preparative workflows, with chromatograms comparing our and competitor's column performances.