Blossmate Chiral Series
Your Chiral Separation Partner - One Platform, All Scales.
High Selectivity, High Loading Capacity, Consistent and Reproducible Results.
Welch Blossmate chiral stationary phases are designed for high-performance enantiomeric separations in analytical, preparative, and bulk purification scale. Available in both coated and immobilized polysaccharide phases, Blossmate chiral series products deliver selectivity, reproducibility, and scalability from R&D through commercial purification.
Blossmate Chiral Phase Overview
| Welch Chiral Product | Phase | Structure | Type | Equivalent |
|---|---|---|---|---|
| Blossmate Amy-D | Amylose tris(3,5-dimethylphenyl carbamate) |
 |
Coated | AD |
| Blossmate Cellu-D | Cellulose tris(3,5-dimethylphenyl carbamate) |
 |
Coated | OD |
| Blossmate Amy-S | Amylose tris((S)-α-methylbenzyl carbamate) |
 |
Coated | AS |
| Blossmate Cellu-J | Cellulose tris(4-methylbenzoate) |
 |
Coated | OJ |
| Blossmate Cellu-Z | Cellulose tris(3-chloro-4-methylphenyl carbamate) |
 |
Coated | OZ |
| Blossmate IMMA | Amylose tris(3,5-dimethylphenyl carbamate) |
 |
Immobilized | IA |
| Blossmate IMMB | Cellulose tris(3,5-dimethylphenyl carbamate) |
 |
Immobilized | IB |
| Blossmate IMMC | Cellulose tris(3,5-dichlorophenyl carbamate) |
 |
Immobilized | IC |
| Blossmate IMMG | Amylose tris(3-chloro-5-methylphenyl carbamte) |
 |
Immobilized | IG |
Key Advantages
- Excellent selectivity: polysaccharide-based CSPs provide superior recognition and resolution across a wide range of chiral molecules.
- High efficiency & superior separation: achieve strong peak shape, high plate count and consistent reproducibility.
- Scale-up capability: Available in analytical columns, preparative columns, and bulk media for seamless process development to production.
- SFC and HPLC compatibility: All preparative column hardware is compatible with SFC; no separate hardware required.
Modes of Use
Blossmate chiral columns and media support the full range of commonly used chiral separation modes: normal-phase, reversed-phase, polar organic, and SFC (supercritical fluid chromatography), enabling flexible method development for both polar and nonpolar targets.
Mode Switching from NP to RP
While Blossmate chiral phases can operate in both NP and RP, once switched from NP to RP, that column should remain dedicated for RP only.
Recommended conditioning before switching:
- Test the column in NP mode to confirm performance.
- Flush with isopropanol at 0.25 mL/min (4.6 mm ID) for 20 minutes.
- Then flush with methanol.
- Transition to RP using aqueous methanol or aqueous acetonitrile.
Brand: Blossmate
Phase: OZ-RH
Particle Size: 5µm
Pore Size:
USP Classification: L123
Separation Mode: Reversed Mode
pH Range:
Surface Area:
Carbon Load:
Max.Pressure: 30MPa
Endcapped:
Max.Temp.: 0-40℃
Particle Shape: Spherical
Column Cross Reference:
(Please kindly note that columns among brands are never 100% the same. The below cross reference list indicates alternatives column(s) that will likely give a similar selectivity. Inevitable differences in retention time, resolution and theoretical plate count exist and may affect the results for certain circumstances.)
Blossmate Chiral Series
Your Chiral Separation Partner - One Platform, All Scales.
High Selectivity, High Loading Capacity, Consistent and Reproducible Results.
Welch Blossmate chiral stationary phases are designed for high-performance enantiomeric separations in analytical, preparative, and bulk purification scale. Available in both coated and immobilized polysaccharide phases, Blossmate chiral series products deliver selectivity, reproducibility, and scalability from R&D through commercial purification.
Blossmate Chiral Phase Overview
| Welch Chiral Product | Phase | Structure | Type | Equivalent |
|---|---|---|---|---|
| Blossmate Amy-D | Amylose tris(3,5-dimethylphenyl carbamate) |
|
Coated | AD |
| Blossmate Cellu-D | Cellulose tris(3,5-dimethylphenyl carbamate) |
|
Coated | OD |
| Blossmate Amy-S | Amylose tris((S)-α-methylbenzyl carbamate) |
|
Coated | AS |
| Blossmate Cellu-J | Cellulose tris(4-methylbenzoate) |
|
Coated | OJ |
| Blossmate Cellu-Z | Cellulose tris(3-chloro-4-methylphenyl carbamate) |
|
Coated | OZ |
| Blossmate IMMA | Amylose tris(3,5-dimethylphenyl carbamate) |
|
Immobilized | IA |
| Blossmate IMMB | Cellulose tris(3,5-dimethylphenyl carbamate) |
|
Immobilized | IB |
| Blossmate IMMC | Cellulose tris(3,5-dichlorophenyl carbamate) |
|
Immobilized | IC |
| Blossmate IMMG | Amylose tris(3-chloro-5-methylphenyl carbamte) |
|
Immobilized | IG |
Key Advantages
- Excellent selectivity: polysaccharide-based CSPs provide superior recognition and resolution across a wide range of chiral molecules.
- High efficiency & superior separation: achieve strong peak shape, high plate count and consistent reproducibility.
- Scale-up capability: Available in analytical columns, preparative columns, and bulk media for seamless process development to production.
- SFC and HPLC compatibility: All preparative column hardware is compatible with SFC; no separate hardware required.
Modes of Use
Blossmate chiral columns and media support the full range of commonly used chiral separation modes: normal-phase, reversed-phase, polar organic, and SFC (supercritical fluid chromatography), enabling flexible method development for both polar and nonpolar targets.
Mode Switching from NP to RP
While Blossmate chiral phases can operate in both NP and RP, once switched from NP to RP, that column should remain dedicated for RP only.
Recommended conditioning before switching:
- Test the column in NP mode to confirm performance.
- Flush with isopropanol at 0.25 mL/min (4.6 mm ID) for 20 minutes.
- Then flush with methanol.
- Transition to RP using aqueous methanol or aqueous acetonitrile.
Brand: Blossmate
Phase: OZ-RH
Particle Size: 5µm
Pore Size:
USP Classification: L123
Separation Mode: Reversed Mode
pH Range:
Surface Area:
Carbon Load:
Max.Pressure: 30MPa
Endcapped:
Max.Temp.: 0-40℃
Particle Shape: Spherical
Column Cross Reference:
(Please kindly note that columns among brands are never 100% the same. The below cross reference list indicates alternatives column(s) that will likely give a similar selectivity. Inevitable differences in retention time, resolution and theoretical plate count exist and may affect the results for certain circumstances.)