Welch products introduction

Xtimate Hybrid Silica Series

Xtimate HPLC column derives its outstanding performance from a special hybrid partic le based technique, which coats a unique 5nm organic/inorganic polymer layer on the silica surface, so that the pH range is extended to 1.0-12.5.
Xtimate column is designed for HPLC method development. Regardless of the types of mobile phase or high temperature, Xtimate HPLC column always has stable performance and long lifetime.

X features of Xtimate column

  • eXtra pH range: wide pH range from 1.0 to 12.5, excellent peak shape for strong bases
  • eXtra column lifetime: 5 times of similar product such as Gemini
  • eXtra performance: column efficiency of 5μm columns is as high as 90000/m, 2-3 times of that of Xterra
  • eXtra care from Welch: enjoy excellent pre-sales and after-sales service from Welch

    SEM Pictures of Ultisil Particles

    Comparison of Peak Shape After Soaking In Base

    After test at pH 12 condition for 4h, the peak shape of hybrid particles based Xtimate column shows no difference.
    Ultisil XB-C18 provides good peak shapes in the separation of these three compounds under pH 7.6, which indicates Ultisil silica contains hardly any metals.

    Lifetime Test Comparison: 5 Times Longer Than Gemini

    Unprecedented Peak Shape

    At mid pH, strong bases usually exhibit bad tailing due to secondary interactions between the analytes and the surface silaols. In Welch’s unique technique, the hybrid layer totally covers the surface silanols and blocks analytes’ access to these surface silanols. Improved bonding and endcapping further reduce silanol activity. As a result, hybrid particle based Xtimate columns show unprecedented peak shape.