Ultisil Ion Exchange columns and media are silica based strong anion exchange (SAX – ammonium-functionalized silane) and strong cation exchange (SCX – covalently bonded aromatic sulfonic acid moiety) columns – with high resolution and high efficiency.

  • Organic modifiers such as acetonitrile and methanol may be used with SAX and SCX columns, within organic/buffer solubility constraintsVery lipophilic
  • Retention can be controlled by varying pH, ionic strength and organic modifier content.

Column Parameters

ColumnsUSPpH rangeCarbon Loading(%)Surface Area(m2/g)EndcappedMax. Temp.(°C)
Ultisil XB-SAXL14 2.0-8.0 7.5(120Å), 1.5(300 Å)320(120Å), 90(300 Å) No 60(pH≤6.5), 40(pH>6.5)
Ultisil XB-SCXL92.0-8.012(120Å), 5(300Å)320(120Å), 90(300 Å)No60(pH≤6.5), 40(pH>6.5)


13 Heparin Disaccharides

ColumnUltisil XB-SAX, 3.0 ×250mm, 5µm
Injection Volume10 µL
Flow rate0.45mL/min
Detector234 nm, 202 nm

Chondroitin Sulfate

ColumnUltisil XB-SAX, 4.6×250mm, 5µm
Mobile PhaseA: water, adjust pH 3.5 with diluted HCl
B: 2 mol/L NaCl, adjust pH 3.5 with diluted HCl
Flow Rate1.0 mL/min
Detector232 nm
Injection Volume20μL
Mixed Standards:Chondroitin disaccharide(B)
6- sulfated chondroitin disaccharide(C)
4- sulfated chondroitin disaccharide(A)

Metformin HCL

ColumnUltisil XB-SCX, 4.6×250mm, 5µm
Mobile Phase:1.7% NH4H2PO4( pH 3.0 adjusted by H3PO4)
Flow rate1.0mL/min
Injection Volume 10μL
Samples In OrderIcyandiamide, melamine, metformin HCL


ColumnUltisil XB-SCX, 4.6×250mm, 5µm
Mobile Phase:1.0% NH4H2PO4( pH 3.0 adjusted by H3PO4)
Flow rate1.0mL/min
Injection Volume 10μL
Samples In OrderOrotic acid, Pyridinepropanimidamide,
hydrochloride and AZO

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About us

Welch Materials is a multinational company that develops and manufactures chromatography consumables including HPLC column, Solid Phase Extraction (SPE) column, GC column, Prep column, Flash column and packing materials.

Our initial strength was our extensive experience on particle surface modification science and techniques. We are experts on bonding
chemistry and innovative packing materials for chromatography applications. Through the optimal utilization of our resources, we have developed many innovative LC and GC consumable products, in particular, our six series HPLC columns, Ultisil®, Welchrom®, Xtimate®, Topsil®, Boltimate® and Blossmate®.