Ultisil Silica-based Series

Ultisil is a broad selection of various stationary phases, each one offering familiar separation behavior in its classification. Upgrade to Ultisil to make it easy to demonstrate equivalence with the phase you might be using currently – plus, you get the Welch Advantages of Purity, Chemistry and Consistency.

Features

  • Ultra-pure spherical porous silica, purity > 99.999%
  • Tested and proven low levels of trace metal contamination
  • Tenaciously-controlled bonding chemistry and end-capping
  • Class-leading reproducibility, efficiency, symmetry, and lifetime

Ultisil XB Reverse Phase

Ultisil XB Reversed Phase materials and columns provide familiar separation behavior, with outstanding efficiency, peak symmetry, reproducibility, and column life.

C18
C8
Phenyl
C4
C1
CN

Ultisil XB Normal Phase

Bare silica, Diol, and NH2 (Amine) are used for normal phase separations; with Diol and NH2 often able to deliver more stable results. Diol and NH2 have the added benefit of reduced sensitivity to the presence of water. Diol and NH2 can also be used in reversed-phase.

SiO2
Diol
NH2

Ultisil XB C30

Compared to conventional C18/ODS phases, Ultisil XB-C30 is far more hydrophobic and retaining. Ultisil XB-C30 is designed for the separation of geometric isomers, polar carotenes, polar and nonpolar xanthophylls, steroids, retinols, and fat-soluble vitamins.

XB-C30

Ultisil IEX

Ultisil Ion Exchange columns and media are silica based strong anion exchange (SAX – ammonium-functionalized silane) and strong cation exchange (SCX – covalently bonded aromatic sulfonic acid moiety) columns – with high resolution and high efficiency.

XB-SAX
XB-SCX

Ultisil Specialized C18

This specialized set of C18 phases is designed to offer nuanced differences from traditional C18/ODS phases. For example, Ultisil AQ-C18 and Ultisil ODS-3 will perform well even with 100% aqueous mobile phase; Ultisil Plus C18 is double-end-capped; Ultisil XS-C18 is high-carbon-loaded, improving its steric hindrance selectivity. Also see specialized C18 phases for Polynuclear Aromatic Hydrocarbons (PAH) and Amino Acid analysis.

Plus C18
Alkyl C18
ODS-3
XS-C18
PAH
Polar-RP
AA-Amino Acid
AQ-C18

Ultisil LP Series

Ultisil LP phases are extremely stable in very low pH mobile phases and at non-typical high temperatures. LP phases use two very bulky hydrophobic protective groups to prevent siloxane bond from hydrolysis at low pH. Excellent peak shape for polar compounds. Stable to UNDER pH = 1 (LP-C18).

LP-C18
LP-C8
LP-AQ
LP-CN
LP-C3

Ultisil Polar Embedded

Compatible with aqueous mobile phases up to 95%, Ultisil Polar Embedded phases provide excellent peak shape for very polar and strong basic compounds – while offering a selectivity different from that of C18. 

Polar-RP
Phenyl-Ether

Ultisil Fluorinated Phases

Fluorinated Phases offer two distinctions. First, they offer increased retention of closely related compounds, including aromatic fluorinated compounds and other nonaromatic halogenated compounds. Second, they can present wholly different retention orders, leading to obvious selectivity benefits with difficult-to-separate compounds.

PFP
F-C8

Ultisil HILIC

Ultisil HILIC phases have been developed for specific use in hydrophilic interaction liquid chromatography where hydrophilic stationary phases are used with mobile phases typically used in reversed-phase, and elution is typically in order of increasing polarity. Each phase in the Ultisil HILIC family has its own distinctive advantages.

HILIC Silica
HILIC NH2
HILIC Amide
HILIC Amphion II
Diol

Ultisil Chiral

Ultisil Chiral Columns offer familiar separation behavior by using cellulose coated silica – Cellu-D employing Cellulose-tris(3, 5-dimethylphenylcarbamate); and Cellu-J using Cellulose tris(4-methylbenzoate). Ultisil Chiral phases are scalable from lab to production.

Cellu-D
Cellu-DR
Cellu-J
Cellu-JR  

Ultisil Mixed Mode Phases

Ultisil Chiral Columns offer familiar Mixed mode phase selectivity is totally different from conventional reversed phase, and separation behavior, while wholly reproducible (typically), is reliant on the method development process. 

MM C18/SCX
MM NH2/CN