UHPLC users have access to a number of high performance choices, including a selection of Ultisil UHPLC (1.8 micron) phases with overlapping selectivity; Xtimate Hybrid UHPLC phases (C18 and C8); and Welch inline filters and guard columns designed for UHPLC applications.  All Welch UHPLC columns feature:

Feature

  • Column bed lengths: 30 mm to 150 mm
  • Column inner diameters: 2.1, 3.0, 4.6 mm
  • All phases available in all sizes
  • Optimized low dead volume
  • UHPLC frit design
  • Optimized packing technique to enable use up to 15,000 psi

Xtimate UHPLC

Xtimate UHPLC C18 (USP L1) is a 1.8 micron hybrid stationary phase synthesized with octadecyl silane. Xtimate UHPLC C18 is 14% carbon loaded, giving it selectivity distinct from Ultisil UHPLC C18. In addition, Xtimate UHPLC C18 provides the widest useful pH range of the UHPLC phases: 1.0 – 12.5 pH.

Ultisil UHPLC Phases

Seven Ultisil Phases for UHPLC include six reversed phase options plus HILIC. Ultisil UHPLC stationary phases are based on 1.8 micron, B ultrapure silica. Higher peak heights and narrower peak widths contribute to improved sensitivity of 70% and 40% compared to 5 micron and 3.5 micron particles.

XB-C18
C18 (USP L1) with standard carbon loading.

AQ-C18
C18 (USP L1) with improved tolerance of aqueous mobile phases.

LP-C18
C18 (USP L1) with improved tolerance of low pH.

XB-C8
C8 (USP L7) is less retentive, as an option for C18.

XB-Phenyl
Alternate selectivity (USP L11) for phenyl groups.

Polar-RP
For very polar and strong basic analytes (USP L60, L1).

HILIC
For hydrophilic interaction liquid chromatography.