An invitation to CPhI China 2019 from Welch Materials

CPhI China 2019 will be hold from 18th-20th June, 2019 at Shanghai New International Expo Centre. Why CPhI? CPhI China 2019 is the gateway to successfully grow business at the 2nd largest pharma market in the world. Together with P-MEC China which focuses on pharmaceutical machinery and equipment, CPhI China is your ONE-STOP SHOP pharmaceutical platform in Asia. The show scale of CPhI & P-MEC China reaches 180,000 m2, while the exhibitor number reaches 3,022 and the Read more…

Hot Wire: Welch Headquarter moves to Tus-Caohejing Science Park

We are pleased to announce that our headquarter will be relocated to the following address as of June 5, 2019: Building 10, Zijing Park, Tus-Caohejing Science Park, No. 85 Mingnan Road, Songjiang District, Shanghai 201613 CHINA We are pleased to announce that our headquarter will be relocated to the following address as of June 5, 2019: Building 10, Zijing Park, Tus-Caohejing Science Park, No. 85 Mingnan Road, Songjiang District, Shanghai 201613 CHINA Tus-Caohejing Science Park(Phase I), opened in May 2016, covers Read more…

Oxidative damage in GC column

Oxygen is a hazardous substance for most of the capillary columns. At room temperature, the column will not be damaged. But as the column temperature increases, the column will be severely damaged. It is important to be noted that polar GC columns will be severely damaged at low oxygen concentrations. Part.1 Apparent phenomena of oxidative damage and influence on analysis ● Influence on column efficiency The column can still be used when it is not severely damaged, but column efficiency will be reduced. Comparison of column evaluation report Normal Chromatogram Chromatogram after oxidative damage ● Influence on resolution The column can not be used Read more…

Core-shell column:get high efficiency at low pressure

Superior core-shell column There are mainly two kinds of chromatographic packing materials: silica gel and polymer. Their structural difference makes maintenance and separation results different. Silica based packing materials contain fully porous silica, ethyl bridged hybrid silica, monolithic silica and core-shell silica. Ultra-efficient analytical results of UHPLC can be obtained on a HPLC instrument with a core-shell silica column. Of course, it will be awesome if core-shell column is used on UHPLC instruments. The core-shell silica consists of a hard core and a porous shell. During Read more…

Amino(NH2) column: How to keep high performance?

When use the amino((NH2) column for a period of time, do you encounter a decrease in column efficiency and an increase in column pressure?Or abnormal interference peaks and the retention time drifts? Or method can’t be reproduced under certain chromatographic conditions? Or the resolution, plates and tailing factor can’t meet the detection requirements? The uniqueness of the NH2 column has caused us a lot of trouble, so today we will discuss about the NH2 column. The bonding Read more…

Welch columns were included in the database of USP-PQRI

The United States Pharmacopoeia (USP) is a recognized statutory public standard setting agency in the United States of America. USP develops quality standards for prescription and OTC medicines, food supplements, and other health care products and works with healthcare organizations to help them to meet standards. For 198 years of existence, these standards have been recognized & used in more than 130 countries around the world to ensure quality of pharmaceutical services and public health. The Read more…

Batch to Batch Reproducibility? The solution is here!

Today we will bring “Solutions to solve poor reproducibility between batch to batch”. Q How to ensure good reproducibility when a new validated HPLC method is transferred to Q.C. lab? HPLC column’s reproducibility is very important if a method will be used for a long time. It is necessary to confirm that the column is stable supplied, which means to choose a reliable HPLC column manufacturer and a common stationary phase instead of special or less used stationary phases. Column specifications and batch to batch reproducibility information should Read more…