Baseline drift can be a real headache for researchers and analysts working with data. It refers to the gradual and undesirable changes in the baseline signal of a measurement, which can obscure or distort the true variations in the data over time. Common causes of baseline drift include changes in temperature, pressure, humidity, or instrument performance, as well as sample evaporation or degradation. Here we have listed some common problems of baseline drift for you.  Read more…

Have you ever encountered issues such as fronting, peak broadening, splitting, etc. during liquid phase system analysis? Why does reducing the injection amount of the same sample sometimes result in a better-looking chromatographic peak? In daily analysis work, we usually focus more on the selection of mobile phase and instrument methods, and neglect the importance of sample injection solvents. If the solvent selection is improper, it will lead to “solvent effects”, causing errors in qualitative Read more…

Solid-phase extraction, abbreviated as SPE, is a sample pre-treatment device developed from chromatographic columns for extraction, separation, and concentration. It is developed by combining liquid-solid extraction cartridges with liquid chromatography technology and is mainly used for sample separation, purification, and concentration. Compared with traditional liquid-liquid extraction methods, SPE can improve the recovery rate of analytes, more effectively separate analytes from interfering components, reduce sample preparation processes, and is simple, time-saving, and labor-saving to operate. It Read more…

For chemical experiments, all results are typically stage-dependent, which involves issues of sample storage and sampling, as well as how to choose appropriate HPLC Vials based on the characteristics of the samples themselves to minimize experimental errors and save costs. Sample Vials include HPLC vials, headspace vials, storage vials, TOC vials, etc. This time, we mainly introduce the selection method of injection vials. 01 SEALING METHODS FOR SAMPLE VIALS Screw thread Cap: a sealing method that Read more…