Do you still feel tired about complicated and time-consuming sample preparation? In pursuit of more efficient and faster sample pretreatment, Welch launched a new generation of product- SinCHERS pretreatment purification column.
Compared with traditional SPE technology, SinCHERS column greatly improved detection efficiency. Compared with the QuEChERS, its purification process does not require centrifugation again and it only needs one step (30s) to complete the purification process. The development of electric supporting equipment enables the whole purification process to be semi-automated. The purification of 12 samples can be completed within 3 minutes, which greatly improves the detection efficiency and relatively reduces the detection cost of the laboratory.
SinCHERS:
Meet AOAC 2007.1 and EN 15662 standards
SinCHERS=Single-step +Cheap+Effective+Rugged+Safe
QuEChERS=Quick+Easy+Cheap+Effective+Rugged+Safe
Perfect substitution of QuEChERS
| SPE | SinCHERS | QuEChERS | SinCHERS advantages | |
| Detection limit | √ √ | √ | √ | 8 times sample concentration can be achieved at most |
| Purification efficiency | × | √ √ | √ | Complete the purification process in one step |
| Purification effect | √ √ | √ √ | × | Extract flows slowly through the purified packing materials, and the impurities are absorbed completely |
| Solvent required | × | √ √ | √ | One sample consumed only 10mI of organic solvent |
Appearance and structure of SinCHERS
Gas vent
Used to drain the volume of air occupied by the organic extract
Reservoir
Used to store purified extract
Guide plate
SinCHERS column body plays a guiding role in the descending process inside centrifugal tube
Block water neck
Water-blocking filter inside prevents water from contacting packing materials and entering the liquid collection tank
Sealing ring
Used for sealing between SinCHERS column body and centrifuge tube
The internal structure of SinCHERS column:
Porous filter
Porous polyethylene filter for fixing packing materials
Packing materials
Adsorb dissolved impurities in the organic extract and purify the extract
Water-blocking filter
Water-blocking groups are bonded to prevent water from passing through
Funnel for collecting liquid
Funnel-shaped bottom to ensure that all organic extracts enter the packing
Operation steps:
1. Extract
● Weigh the sample in the centrifuge tube
● Add acetonitrile.
● Ultrasound or homogenizer extraction, completely release the components to be tested in the sample.
● Add buffer salt or excessive salt to the centrifuge tube.
● Vibrate.
● Centrifuge.
The centrifugation time shall not be less than 3min.
2. Clean
●Insert SinCHERS column into the centrifuge tube.
● Press down slowly at the speed at 2mm/s.
● The upper organic extract in the centrifuge tube will contact with the packing materials through the water-blocking filter. Impurities and interferents will be adsorbed by the packing and the components to be tested will enter into the reservoir.
● Continue to press down the SinCHERS column until it cannot be descended. The process is completed. Take out the tested liquid into the sample vial for testing.
● You can choose to use manual tools or power tools to complete the downpressing process of SinCHERS in a centrifugal tube (find details in product materials).
| P/N | Product | Specification |
| 01140-10011 | Welchrom®SinCHERS column | Welchrom®SinCHERS-AZO, 30 pk (include centrifuge tube) |
| 01140-10021 | Welchrom®SinCHERS column | Welchrom®SinCHERS-F, 30 pk (include centrifuge tube) |
| 01140-10031 | Welchrom®SinCHERS column | Welchrom®SinCHERS-General, 1200 mg MgSO4, 400 mg PSA, 400 mg C18, 30pk (include centrifuge tube) |
| 01140-10041 | Welchrom®SinCHERS column | Welchrom®SinCHERS-PC, 30pk (include centrifuge tube) |
| 01140-10051 | Welchrom®SinCHERS column | Welchrom®SinCHERS-General, 1200mg MgSO4, 400mg PSA, 400mg C18, 200mg GCB-200A, 30pk (include centrifuge tube) |
| 01140-10061 | Welchrom®SinCHERS column | Welchrom®SinCHERS-Herb, 900mg MgSO4,400mg PSA, 400mg C18, 400mg POLY, 200mg GCB-100A, 30 pk (include centrifuge tube) |
| 01140-10071 | Welchrom®SinCHERS column | Welchrom®SinCHERS-Lipid, Special for removing the lipid, 30 pk(include centrifuge tube) |
| 01140-10081 | Welchrom®SinCHERS column | Welchrom®SinCHERS-ANT I, 30 pk (include centrifuge tube) |
| 01140-10091 | Welchrom®SinCHERS column | Welchrom®SinCHERS-ANT II, 30 pk (include centrifuge tube) |
| 01140-20001 | Auxiliary tool | Manual tool |
| 01140-20002 | Auxiliary tool | Power tool, four ports |
| 00530-20000 | Salt bag | 4g magnesium sulfate, 1g sodium chloride, 50 pk |
| 00529-20000 | Salt bag | 4g magnesium sulfate, 1g sodium citrate, 0.5g disodium citrate, 1g sodium chloride, 50 pk |
| 00528-20000 | Salt bag | 6g magnesium sulfate, 1.5g sodium acetate, 50 pk |
| 005PM-059-50 | Salt bag | 4.0g anhydrous sodium sulfate, 1.0g sodium chloride, 50 pk |
| 005PM-104-50 | Salt bag | 8g sodium chloride, 50 pk |
If you have any problem or require further information, please contact info@welchmat.com.
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