Determination of Related Substances in Amoxicillin and Clavulanate Potassium Granules by Xtiamte C18

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ColumnXtimate® C18（4.6×150mm，5μm)
Mobile PhaseMobile phase A: 0.01 mol/L Potassium Dihydrogen Phosphate Solution (pH 6.0 adjusted with 2 mol/L Sodium Hydroxide Solution). Mobile phase B: 0.01mol/L potassium dihydrogen phosphate solution (adjusted with 2mol/L sodium hydroxide solution section pH6.0)/acetonitrile=20/80
Detection230nm
Temperature35℃
Flow Rate1.0ml/min
Injection Volume20 μL
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