Determination of related substances and content of metformin hydrochloride enteric-coated
capsules by Xtiamte C18

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ColumnXtimate® C18（4.6×150mm，5μm)
Mobile Phase0.05% sodium heptanesulfonate solution/acetonitrile=84/16
Detection218nm (related substances)/233nm (content determination)
Temperature35℃
Flow Rate1.0 ml/min
Injection Volume20 μL

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