In the course of using liquid chromatography columns, issues such as contamination and wear are inevitable. In such cases, it becomes necessary to perform essential rinsing and maintenance on the chromatography columns. From the perspective of the bonded phases used, liquid chromatography columns can generally be divided into reverse-phase and Read more…
01 What is Normal Phase Chromatography? Liquid chromatography encompasses several separation modes, with normal phase chromatography being one of the earliest developed. Its distinguishing feature is that the polarity of the stationary phase in the chromatographic column is greater than that of the mobile phase. Normal phase chromatography primarily relies Read more…
Welchrom® PBA Benzenboronic Acid Column is part of Welch Materials’ specialized pre-processing column series, featuring a novel solid-phase extraction adsorbent designed for the efficient purification of ribavirin samples. It plays a crucial role in the food industry, primarily employed for ribavirin residue analysis in animal-derived food products, enhancing analytical sensitivity, Read more…
As industry standards continue to advance, analytical instruments are becoming more sensitive with lower detection limits. Concurrently, there is a corresponding increase in the water quality requirements for laboratory use. Conventional bottled water and purified water are gradually proving inadequate to meet the demands of analytical testing, leading more users Read more…
In the process of chromatographic analysis, one may observe that for certain compounds, using an older chromatography column yields better peak shapes and separation compared to when a new column is employed. This phenomenon of ‘new doesn’t always mean better; it gets better with use!’ can be attributed to the Read more…
Liquid Chromatography Instruments are commonly used in our labs, with the pump being a crucial component. Learn how to optimize your liquid chromatography usage and perform effective pump maintenance with us. Degassing Unit Purge Valve and Proportioning Valve One-Way Valves One-way Valve, Used to Prevent Reverse Flow of Mobile Phase Read more…
In the process of reversed-phase chromatographic separation, it is essential for the analyte to maintain an appropriate and stable molecular/ion equilibrium state to ensure the effectiveness of chromatographic separation. However, do ionic compounds really behave so ‘honestly’ once they enter the chromatographic column? The presence of silanol groups in the Read more…
What is Spiking Recovery? Spiking recovery refers to the addition of a known quantity of a standard substance into the sample matrix of the substance under analysis. Following identical sample processing steps, the obtained result is then compared to the theoretical value. In experiments, the magnitude of spiking recovery not Read more…
“Diamond Like Carbon Chromatography Columns” A groundbreaking new product, now officially available! September 15, 2023 What is a diamond chromatography column? Is it related to actual diamonds? Where does the brilliance on the surface of the diamond column come from? What are the unique performance characteristics of a diamond column? Read more…
Hello, everyone! Have you ever encountered situations in your daily work where it’s challenging to analyze certain compounds using conventional experimental methods? What should we do in such cases? Derivatization is a great option to consider. Today, join me to explore the application of derivative techniques in liquid chromatography. Let’s Read more…